⒉Transgenic avian bioreactor
Biopharmaceuticals such as monoclonal antibodies and erythropoietin have been produced mainly by recombinant animal cell cultures.
However, the production cost in animal cell cultures is very high even though genetic engineering and culture technology have well developed.
In recent years, transgenic bioreactors have been proposed as a novel production system for biopharmaceutical proteins.
We have developed various techniques to generate transgenic avian species for the production of biopharmaceuticals into eggs, and we have attempted to produce recombinant proteins using transgenic avian bioreactors.